alexa Cardiovascular fitness after stroke: Role of muscle mass and gait deficit severity.
Neurology

Neurology

International Journal of Neurorehabilitation

Author(s): Ryan AS, Dobrovolny CL, Silver KH, Smith GV, Macko RF

Abstract Share this page

Abstract Functional disability after hemiparetic stroke may be compounded by physical deconditioning and muscular wasting, factors related to disuse and advancing age. However, the role of body composition, severity, and chronicity of gait deficits as determinants of exercise fitness after stroke is unknown. The purpose of this study was to determine whether oxygen consumption during peak exercise (VO2 peak) is associated with body composition, the severity, or duration of gait deficits in chronic (>6 months) hemiparetic stroke patients. Twenty-six patients (22 men, 4 women), aged 66 ± 9 years (mean ± standard deviation [SD]), completed a progressive graded treadmill test until fatigue to measure VO2 peak (1.3 ± 0.4 L/minute). Timed 30-foot walks were used to determine self-selected floor walking velocity (0.63 ± 0.31 m/s), an index of gait deficit severity. Percent body fat (30.4\% ± 10.6\%), total lean mass (52.0 ± 9.3 kg), lean mass of the paretic and nonaffected legs (17.2 ± 3.7 kg), and lean mass of the paretic and nonaffected thighs (13.2 ± 2.7 kg) were determined by dual-energy x-ray absorptiometry. Total lean mass (r = 0.60), lean mass of both legs (r = 0.58), paretic leg lean mass (r = 0.55), lean mass of both thighs (r = 0.64), and self-selected floor walking velocity (r = 0.53, all P < .01) correlated with VO2 peak. In contrast, percent body fat and latency since index stroke were unrelated to VO2 peak. In a stepwise regression analysis, lean mass of both thighs (r = 0.64, P < .001) and self-selected walking velocity (cumulative r = 0.78, P < .001) were independent predictors of VO2 peak and explained 61\% of the variance. These results suggest that hemiparetic stroke patients are profoundly deconditioned, regardless of the latency since stroke, and that lower lean thigh mass and greater gait deficit severity predict even poorer peak exercise capacity. Copyright © 2000 National Stroke Association. Published by Elsevier Inc. All rights reserved. This article was published in J Stroke Cerebrovasc Dis and referenced in International Journal of Neurorehabilitation

Relevant Expert PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords