Author(s): Harris J, Werling D, Hope JC, Taylor G, Howard CJ, Harris J, Werling D, Hope JC, Taylor G, Howard CJ
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Abstract Caveolae are small, cholesterol-rich, hydrophobic membrane domains, characterized by the presence of the protein caveolin and involved in several cellular processes, including clathrin-independent endocytosis, the regulation and transport of cellular cholesterol, and signal transduction. Recently, caveolae have been identified as providing a novel route by which several pathogens are internalized by antigen-presenting cells and as centers for signal transduction. Here, we review the distribution and role of caveolae and caveolin in mammalian immune cells.
This article was published in Trends Immunol
and referenced in Immunome Research