alexa CCR2 64I mutation detection in a HIV-1-positive patient with slow CD4 T-cell decline and delay in disease progression.
Healthcare

Healthcare

Health Care : Current Reviews

Author(s): Burton CT, Gotch FM, Imami N

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Abstract Chemokine receptor genetic mutations are among the factors which have been shown to influence human susceptibility to HIV-1 infection and progression. The CCR2-64I mutation has been shown to delay HIV-1 disease progression in some studies. Here we show evidence of delayed disease progression, reflected in maintenance of a stable viral load and a slow CD4 T-cell decline, in a patient with the CCR2-64I gene. We then consider the potential value of identifying these genetic defects in the era of fusion/entry inhibiting therapeutics. This article was published in Int J STD AIDS and referenced in Health Care : Current Reviews

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