alexa CD8(+) T cells in leishmania infections: friends or foes?


Journal of Microbial & Biochemical Technology

Author(s): Stger S, Rafati S, Stger S, Rafati S

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Abstract Host protection against several intracellular pathogens requires the induction of CD8(+) T cell responses. CD8(+) T cells are potent effector cells that can produce high amounts of pro-inflammatory cytokines and kill infected target cells efficiently. However, a protective role for CD8(+) T cells during Leishmania infections is still controversial and largely depends on the infection model. In this review, we discuss the role of CD8(+) T cells during various types of Leishmania infections, following vaccination, and as potential immunotherapeutic targets.
This article was published in Front Immunol and referenced in Journal of Microbial & Biochemical Technology

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