alexa Cellular and molecular mechanisms of drug dependence.


Journal of Addiction Research & Therapy

Author(s): Koob GF, Bloom FE

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Abstract The molecular and cellular actions of three classes of abused drugs--opiates, psychostimulants, and ethanol--are reviewed in the context of behavioral studies of drug dependence. The immediate effects of drugs are compared to those observed after long-term exposure. A neurobiological basis for drug dependence is proposed from the linkage between the cellular and behavioral effects of these drugs.
This article was published in Science and referenced in Journal of Addiction Research & Therapy

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