alexa Cellular reprogramming: chromatin puts on the brake.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Genetic Syndromes & Gene Therapy

Author(s): Sengupta P, Schedl T

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Abstract Directed reprogramming of differentiated cells allows the generation of specific cell types for therapeutics and can provide unexpected insights into development. A recent study demonstrates that efficient reprogramming of Caenorhabditis elegans germ cells into neurons can be achieved by knocking down a histone chaperone gene and ectopic expression of a terminal selector transcription factor. Copyright © 2011 Elsevier Ltd. All rights reserved. This article was published in Curr Biol and referenced in Journal of Genetic Syndromes & Gene Therapy

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