alexa Cerebellar astrocytomas: a 24-year experience.


Journal of Brain Tumors & Neurooncology

Author(s): Viano JC, Herrera EJ, Surez JC

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Abstract INTRODUCTION: Cerebellar astrocytomas are the most benign tumors of the CNS. Seventy to eighty percent are found in children. METHODS AND RESULTS: We report on 38 children under 18 who had cerebellar astrocytoma in the posterior fossa and were treated by a multidisciplinary team in our Neurosurgical Department from January 1974 to December 1997. We included all patients in whom the histopathological diagnosis was astrocytoma, regardless of malignancy. The diagnostic methods used were pneumoventriculography, cranial X-rays, CT scan, and MRI. All patients were treated surgically. Neither radiotherapy nor chemotherapy was indicated in patients with pilocytic or fibrillary astrocytomas. A greater prevalence was observed in female (25/38; 66\%) than in male (13/38; 34\%) patients. Histopathological results revealed 27 (71\%) pilocytic astrocytomas, 8 (21\%) diffuse fibrillary astrocytomas, 1 (2\%) anaplastic astrocytoma and 2 (6\%) glioblastomas. These tumors were more frequently located in the right cerebellar hemisphere; increased intracranial pressure syndrome was the most frequent form of clinical presentation. Total tumor resection was obtained in 29 (83\%) cases and subtotal resection in 9 (17\%). In 6 (16\%) cases, ventriculoperitoneal shunts were placed to control persistent hydrocephalus after tumor excision. CONCLUSION: The most frequent complication was increased ataxia. The mortality rate was 8.5\%. This article was published in Childs Nerv Syst and referenced in Journal of Brain Tumors & Neurooncology

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