Author(s): Gondo A, Saeki N, Tokuda Y
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Abstract We succeeded in reproducing an eczematous lesion on the apparently normal skin of a patient with atopic dermatitis by scratching and continuous application of an ointment containing ferritin-labelled mite antigen. Percutaneous entry of mite antigen was demonstrated in skin biopsies by Fe-staining. Scratched skin first showed an urticarial reaction typical of type I allergy which later changed into an eczematous reaction typical of type IV allergy. This change was also shown histologically.
This article was published in Br J Dermatol
and referenced in International Journal of Inflammation, Cancer and Integrative Therapy