Author(s): Gallant JE, Parish MA, Keruly JC, Moore RD, Gallant JE, Parish MA, Keruly JC, Moore RD
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Abstract In our large observational cohort, use of tenofovir disoproxil fumarate (n=344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n=314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of therapy.
This article was published in Clin Infect Dis
and referenced in Journal of AIDS & Clinical Research