alexa Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment.
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Gallant JE, Parish MA, Keruly JC, Moore RD, Gallant JE, Parish MA, Keruly JC, Moore RD

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Abstract In our large observational cohort, use of tenofovir disoproxil fumarate (n=344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n=314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of therapy. This article was published in Clin Infect Dis and referenced in Journal of AIDS & Clinical Research

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