alexa Chemiluminescence sensor for isoniazid with controlled-reagent-release technology.
Pharmaceutical Sciences

Pharmaceutical Sciences

Pharmaceutica Analytica Acta

Author(s): Song Z, L J, Zhao T

Abstract Share this page

Abstract A novel chemiluminescence (CL) sensor for isoniazid combined with flow-injection technology is presented in this paper. The analytical reagents, luminol and ferricyanide, were both immobilized on an anion-exchange column. The CL signal produced by the reaction between luminol and ferricyanide, which were eluted from the column through sodium phosphate injection, was decreased in the presence of isoniazid. The decreased CL intensity was linear with isoniazid concentration in the range 0.001-1.0 mug.ml(-1); and the detection limit was 0.35 ng.ml(-1) (3s). The whole process, including sampling and washing, could be completed in 2 min with a relative standard deviation of less than 4.1\%. The sensor could be reused more than 400 times and has been applied for the determination of isoniazid in pharmaceutical preparations.
This article was published in Talanta and referenced in Pharmaceutica Analytica Acta

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords