alexa Childhood optic neuritis clinical features and outcome.
Pediatrics

Pediatrics

Journal of Pediatric Neurological Disorders

Author(s): Tintore M, SastreGarriga J, Absoud M, Cummins C, Desai N, Gika A, McSweeney N,

Abstract Share this page

Abstract AIM: To describe clinical features and outcome of a series of children with first-episode optic neuritis investigated in three paediatric neurology centres. METHODS: Databases were searched to identify children (<16 years) with optic neuritis and life table analysis was used. RESULTS: 44 children (female/male ratio 1.8) median age 10.9 years were followed up for median 1 year. Optic neuritis was unilateral in 43\%. Maximal visual deficit was severe (<6/60) in 77\%, with full recovery in 70\%. Cumulative probability of developing MS (11/44) or NMO (3/44) at 2 years was 0.45. Relapsing optic neuritis was a strong predictor for development of MS or NMO. A positive MRI (>1 brain T2 hyperintense lesion) was a strong predictor for development of MS. DISCUSSION: Childhood optic neuritis is associated with severe visual deficit with good recovery. An initial abnormal MRI brain scan or relapsing optic neuritis should alert the clinician to MS or NMO diagnosis. This article was published in Arch Dis Child and referenced in Journal of Pediatric Neurological Disorders

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords