Author(s): Porter DL, Kalos M, Zheng Z, Levine B, June C
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Abstract We presented data showing that the CART-19 cells expressing the 4-1BB signaling domain can have unprecedented and massive in-vivo expansion, traffic to tumor sites, persist long term in vivo, and induce rapid and potent anti-tumor activity in chemotherapy refractory CLL patients.
This article was published in J Cancer
and referenced in Journal of Cancer Research and Immuno-Oncology