alexa Chloroplast-derived anthrax and other vaccine antigens: their immunogenic and immunoprotective properties.
Agri and Aquaculture

Agri and Aquaculture

Advances in Crop Science and Technology

Author(s): Kamarajugadda S, Daniell H

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Abstract Transgenic plants offer many advantages, including low cost of production (by elimination of fermenters), storage and transportation, heat stability, absence of human pathogens, protection of antigens in the stomach through bioencapsulation (when delivered orally), elimination of the need for expensive purification and sterile injections and generation of both systemic and mucosal immunity. Recent studies have demonstrated that chloroplast-derived anthrax-protective antigen elicits effective immune responses, develops neutralizing antibodies, confers complete protection against anthrax lethal toxin challenge and produces 360 million doses of vaccine in one acre of transgenic plants. Chloroplast-derived vaccine antigens are efficacious against bacterial, fungal, viral and protozoan pathogens. This article was published in Expert Rev Vaccines and referenced in Advances in Crop Science and Technology

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