Author(s): Kreusel KM, Wiegel T, Stange M, Bornfeld N, Hinkelbein W,
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Abstract PURPOSE: To determine frequency, risk factors, and benefit of a prospective screening for intraocular metastasis in patients with metastatic lung cancer. DESIGN: Consecutive observational case series. METHODS: An ophthalmologic screening was performed on 84 consecutive patients suffering from metastatic lung cancer. Medical history and disease stage were evaluated in regard to the risk for intraocular metastasis. RESULTS: In six patients (7.1\%) choroidal metastasis (CM) was detected. Choroidal metastasis was present only when at least two other organ system were affected by metastasis (P =.03). The choroid was the sixth common site of organ metastasis. Mean remaining life span in patients with CM was 1.9 (0.2-5.9) months. CONCLUSIONS: Choroidal metastasis is common in advanced metastatic lung cancer. However, due to the short survival of affected individuals, a systematic screening of at-risk patients for CM seems to be of limited benefit.
This article was published in Am J Ophthalmol
and referenced in Journal of Analytical & Bioanalytical Techniques