Author(s): Adams RR, Carmena M, Earnshaw WC
Abstract Share this page
Abstract Chromosomal passengers are proteins that move from centromeres to the spindle midzone during mitosis. Recent experiments show that the passengers inner centromere protein (INCENP) and aurora-B kinase are in a macromolecular complex that might also contain a third passenger, survivin. The chromosomal passenger complex functions throughout mitosis in chromosome condensation and segregation, and at the end of mitosis, in the completion of cytokinesis.
This article was published in Trends Cell Biol
and referenced in Journal of Carcinogenesis & Mutagenesis