alexa Chronic cerebrospinal venous insufficiency in Ménière disease.
Neurology

Neurology

Journal of Multiple Sclerosis

Author(s): Di Berardino F, Alpini DC, Bavera PM, Cecconi P, Farabola M,

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Abstract OBJECTIVES: The aim of this study was to focus on patients suffering from cochleo-vestibular disorder with and without Ménière disease (MD) in order to verify whether chronic cerebrospinal drainage abnormalities could play a role in the etiopathogenesis of endolymphatic hydrops. METHODS: Fifty-two volunteers were enrolled and subdivided into two groups: 24 definite MD and 28 not-MD. Both magnetic resonance venography imaging with contrast-enhanced imaging of the venous cerebrospinal system (MRV) and venous echo-color Doppler (ECD) were performed. RESULTS: MRV showed abnormalities in 83\% of MD and 57\% of not-MD subjects (p < 0.001). Asymmetrical cervical venous flow, assessed by MRV, was confirmed by ECD in 62.5\% of MD but in only 21.5\% of not-MD subjects (p<0.001). CONCLUSION: Chronic cerebrospinal venous insufficiency might be the anatomical background, which provides a predisposing factor for the development of endolymphatic hydrops in MD patients. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav. This article was published in Phlebology and referenced in Journal of Multiple Sclerosis

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