alexa Circadian variation in onset of acute ischemic stroke.


Journal of Clinical & Experimental Pathology

Author(s): Marsh EE rd, Biller J, Adams HP Jr, Marler JR, Hulbert JR,

Abstract Share this page

Abstract A circadian pattern for the onset of myocardial and cerebral infarction has been identified. To evaluate this phenomenon further, we analyzed prospectively collected data from 151 patients with acute ischemic stroke. The number of strokes per 6-hour period were the following: midnight to 6 AM, 20 (13\%); 6 AM to noon, 86 (57\%); noon to 6 PM, 21 (14\%); and 6 PM to midnight, 24 (16\%). This pattern was not affected by previous use of aspirin. The most frequent time of onset was 6 AM to noon for all subgroups of ischemic stroke: small artery, 71\%; cardioembolic, 62\%; large artery atherothrombotic, 57\%; large artery atheroembolic, 46\%; and "other" or unknown cause, 40\%. We also investigated the time between awakening and stroke onset in 145 patients and found that 24\% of ischemic strokes occurred within the first hour after awakening. Our data demonstrate that an early morning peak exists for all subtypes of stroke. Our data also suggest that the most critical period is the first hour after awakening.
This article was published in Arch Neurol and referenced in Journal of Clinical & Experimental Pathology

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version