Author(s): Savage JR
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Abstract A detailed survey is given of the types and classification of primary structural changes that can be induced in chromosomes and observed at the first metaphase after the initial damage. Comments upon identification and scoring are given for the benefit of new workers. The annotation concludes with a brief discussion of the potential relationships between the primary types, and the secondary or derived types encountered in clinical studies.
This article was published in J Med Genet
and referenced in Journal of Nuclear Medicine & Radiation Therapy