alexa "Click-fluors": modular fluorescent saccharide sensors based on a 1,2,3-triazole ring.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Glycomics & Lipidomics

Author(s): Scrafton DK, Taylor JE, Mahon MF, Fossey JS, James TD

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Abstract A carbohydrate sensing "click-fluor" is reported which displays a nontypical binding preference with sample saccharides. That a fluorescent sensor is generated as a result of triazole formation (click reaction), rather than simply bringing the sensor and reporter units together via a triazole linkage, and the potential applicability of the wide range of easily accessible acetylene units means a simple strategy for the development of modular fluorescent sensor arrays for rapid screening of target saccharides will be available. This article was published in J Org Chem and referenced in Journal of Glycomics & Lipidomics

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