alexa Clindamycin versus ampicillin in the treatment of odontogenic infections.
Microbiology

Microbiology

Journal of Antimicrobial Agents

Author(s): Mangundjaja S, Hardjawinata K

Abstract Share this page

Abstract The subjects were 106 patients, aged 14 to 70 years, with acute facial or oral abscesses originating from an odontogenic source. They were randomly assigned to receive 150 mg of clindamycin or 250 mg of ampicillin orally four times daily for seven days. After seven days of treatment, the infections were eradicated in 36 of the 52 clindamycin-treated patients and in 42 of the 54 ampicillin-treated patients, and improved in 16 and 11, respectively. One of the ampicillin group was a treatment failure. Mixed bacterial infections were found in most of the patients; 385 isolates were identified, 167 aerobes and 218 anaerobes. The most common aerobes were Staphylococcus aureus (in 58 patients), Staphylococcus epidermidis (in 47), and Staphylococcus viridans (in 32); the most common anaerobes were species of Peptococcus (in 76), Bacteroides (in 38), and Peptostreptococcus (in 33). No isolates were resistant to clindamycin; nine of 126 aerobes and six of 160 anaerobes were resistant to ampicillin. It is concluded that clindamycin is a safe and effective alternative antibiotic in the treatment of odontogenic infections.
This article was published in Clin Ther and referenced in Journal of Antimicrobial Agents

Relevant Expert PPTs

Relevant Speaker PPTs

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords