Author(s): Johansson B
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Abstract BACKGROUND/AIMS: To investigate the incidence of Nd:YAG-laser treatment for posterior capsular opacification (PCO) over a period of 5 years from phacoemulsification in an unselected population, comparing outcomes for three acrylic intraocular lenses (IOLs). METHODS: Retrospective longitudinal cohort study comprising 900 eyes. Three subgroups of 300 eyes, receiving the AR40, AR40e (Abbott Medical Optics, Santa Ana, California), or BL27 (Bausch & Lomb, Rochester, New York) IOL respectively, were compared. Data on patient age, gender, IOL type, dates of cataract surgery, Nd:YAG-laser treatment and/or death, and visual acuities before/after cataract surgery/Nd:YAG-laser treatment were collected from five sources: cataract operation register, patient administration system, quality control system for cataract operations, Nd:YAG-laser treatment register and clinical patient records. RESULTS: 216 eyes (24\%) received Nd:YAG-laser treatment over a 5-year period. Statistically significant differences (p<0.001, chi(2) test) were found between treatment rates for the three IOLs: AR40 73 eyes (24\%), BL27 91 eyes (30\%) and AR40e 52 eyes (17\%). Eyes of patients who died during the follow-up period had fewer treatments (23/266, 8.6\%) than eyes of patients living (193/634, 30\%) at the end of the follow-up period. CONCLUSION: In comparison with a hydrophobic acrylic IOL with sharp posterior optic edge, a hydrophilic acrylic IOL was associated with almost twice the number of Nd:YAG-laser treatments over the 5-year period. The results are useful for discussing the economic long-term consequences of choosing an IOL with a design that makes PCO development more or less likely. Caution is advised when applying data from post-mortem PCO studies on living populations.
This article was published in Br J Ophthalmol
and referenced in Journal of Clinical & Experimental Ophthalmology