Author(s): Petricoin EF, Zoon KC, Kohn EC, Barrett JC, Liotta LA
Abstract Share this page
Abstract The ultimate goal of proteomics is to characterize the information flow through protein networks. This information can be a cause, or a consequence, of disease processes. Clinical proteomics is an exciting new subdiscipline of proteomics that involves the application of proteomic technologies at the bedside, and cancer, in particular, is a model disease for studying such applications. Here, we describe proteomic technologies that are being developed to detect cancer earlier, to discover the next generation of targets and imaging biomarkers, and finally to tailor the therapy to the patient.
This article was published in Nat Rev Drug Discov
and referenced in Journal of Proteomics & Bioinformatics