alexa Clinical strategies for preventing postoperative nausea and vomitting after middle ear surgery in adult patients.


Journal of Anesthesia & Clinical Research

Author(s): Fujii Y

Abstract Share this page

Abstract Middle ear surgery (tympanoplasty and mastoidectomy) performed under general or local anesthesia is associated with a high incidence of postoperative nausea and vomiting (PONV). Between 50\% and 80\% of patients who undergo these surgical procedures experience PONV. Numerous antiemetics have been studied for the prevention of PONV after middle ear surgery. Traditional antiemetics, including anticholinergics (e.g., scopolamine), phenothiazines (e.g., promethazine), butyrophenones (e.g., droperidol), and benzamide (e.g., metoclopramide), are used for the prevention of PONV during 0-24 h after anesthesia. The available nontraditional antiemetics that have been shown to be effective for the prophylaxis against PONV are propofol, dexamethasone, tandospirone, and midazolam. Antiserotinins (ondansetron, granisetron, and ramosetron) are highly effective in decreasing the incidence of PONV for 24 h postoperatively, compared with traditional antiemetics. Ramosetron is effective for the long-term (up to 48 h) prevention of PONV. None of the available antiemetics is entirely effective, perhaps because most of them act through the blockade on one type of receptor. There is a possibility that combined antiemetics with different sites of activity would be more effective than one drug alone for preventing PONV. Nonpharmacological technique is acustimulation at P6 (Nei-Kuwan) point.
This article was published in Curr Drug Saf and referenced in Journal of Anesthesia & Clinical Research

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version