alexa Clinical-pathological determinants in prognosis of fibrous histiocytomas of head and neck.


Journal of Cancer Science & Therapy

Author(s): Blitzer A, Lawson W, Zak FG, Biller HF, Som ML

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Abstract Review of the literature reveals 76 cases of fibrous histiocytoma of the deep structures of the head and neck. To this we have added 11 of our own cases, and analyzed the total group to determine clinical and histological features of a high risk population. Age, sex, presence of pain, location of tumor, size of tumor, and local invasion appear to be important clinical criteria. Bizarre giant cells, numerous and atypical mitoses, necrosis, and inflammation appear to be important histologic features. The treatment of choice is wide local excision. Chemotherapy appears to produce tumor regression.
This article was published in Laryngoscope and referenced in Journal of Cancer Science & Therapy

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