Author(s): Hasegawa M, Yoshida K, Wakabayashi H, Sudo A, Hasegawa M, Yoshida K, Wakabayashi H, Sudo A, Hasegawa M, Yoshida K, Wakabayashi H, Sudo A, Hasegawa M, Yoshida K, Wakabayashi H, Sudo A
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Abstract Seventy-five patients underwent unilateral metal-on-metal total hip arthroplasty using a large-diameter head. Serum levels of cobalt and chromium were determined. Significant increases in both cobalt and chromium were observed at 3 months (cobalt, 1.4 μg/L; chromium, 1.4 μg/L) compared with preoperative values (P < .001). At 1 year, the median cobalt and chromium levels were 2.3 and 2.1 μg/L, respectively, and the levels had increased significantly compared with 3 months (P < .001). There were no significant differences between levels of either metal at 1 or 2 years (cobalt, 2.3 μg/L; chromium, 1.6 μg/L). Pseudotumor occurred in 2 hips. Patients with large-diameter metal-on-metal total hip arthroplasty had higher circulating metal ion levels at 3 months and 1 year, with no additional significant increases at 2 years. Copyright © 2012 Elsevier Inc. All rights reserved.
This article was published in J Arthroplasty
and referenced in Journal of Arthritis