alexa Comparative analysis between Chamomilla recutita and corticosteroids on wound healing. An in vitro and in vivo study.


Journal of Clinical & Cellular Immunology

Author(s): Martins MD, Marques MM, Bussadori SK, Martins MA, Pavesi VC,

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Abstract The comparison of chamomile and corticosteroids for treating ulcers was done in vitro and in vivo. The experimental groups were: control; chamomile recutita; triamcinolone acetonide and clobetasol propionate. For the in vitro study the cell viability of fibroblasts cultured for 24 h in media conditioned by the substances was obtained by the MTT reduction analysis. For the in vivo study, 125 male rats were submitted to experimental ulcers treated or not (control) by the substances tested. At 1, 3, 5, 7 and 14 days later 5 animals of each group were sacrificed. The lesions were analyzed by means of clinical observation and histological wound-healing grading. Data were compared by ANOVA (p
  • DOI: 10.1002/ptr.2612
  • This article was published in Phytother Res and referenced in Journal of Clinical & Cellular Immunology

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