alexa Comparative evaluation of endodontic irrigants against Enterococcus faecalis biofilms.


Transplant Reports : Open Access

Author(s): Dunavant TR, Regan JD, Glickman GN, Solomon ES, Honeyman AL

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Abstract The aim of this study was to compare the efficacy of root canal irrigants against E. faecalis biofilms using a novel in vitro testing system. Biofilms grown in a flow cell system were submerged in test irrigants for either 1 or 5 minutes. Statistical analysis revealed a significant relationship between test agent and percentage kill of the biofilm bacteria (P < 0.05). No statistically significant relationship between time and percentage kill was found. The percentage kill of the biofilm bacteria was: 6\% NaOCl (>99.99\%), 1\% NaOCl (99.78\%), Smear Clear (78.06\%), 2\% chlorhexidine (60.49\%), REDTA (26.99\%), and BioPure MTAD (16.08\%). Post-hoc analysis showed a significant difference between 1\% and 6\% NaOCl, and all other agents including Smear Clear, 2\% chlorhexidine, REDTA, and BioPure MTAD (P < 0.05). Within the parameters of this study, both 1\% NaOCl and 6\% NaOCl were more efficient in eliminating E. faecalis biofilm than the other solutions tested. This article was published in J Endod and referenced in Transplant Reports : Open Access

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