Author(s): Dunavant TR, Regan JD, Glickman GN, Solomon ES, Honeyman AL
Abstract Share this page
Abstract The aim of this study was to compare the efficacy of root canal irrigants against E. faecalis biofilms using a novel in vitro testing system. Biofilms grown in a flow cell system were submerged in test irrigants for either 1 or 5 minutes. Statistical analysis revealed a significant relationship between test agent and percentage kill of the biofilm bacteria (P < 0.05). No statistically significant relationship between time and percentage kill was found. The percentage kill of the biofilm bacteria was: 6\% NaOCl (>99.99\%), 1\% NaOCl (99.78\%), Smear Clear (78.06\%), 2\% chlorhexidine (60.49\%), REDTA (26.99\%), and BioPure MTAD (16.08\%). Post-hoc analysis showed a significant difference between 1\% and 6\% NaOCl, and all other agents including Smear Clear, 2\% chlorhexidine, REDTA, and BioPure MTAD (P < 0.05). Within the parameters of this study, both 1\% NaOCl and 6\% NaOCl were more efficient in eliminating E. faecalis biofilm than the other solutions tested.
This article was published in J Endod
and referenced in Transplant Reports : Open Access