Author(s): Ablordey A, Hilty M, Stragier P, Swings J, Portaels F
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Abstract We analyzed a set of variable-number tandem-repeat (VNTR) loci to assess their nucleotide sequence diversity in isolates of three Mycobacterium ulcerans genotypes. Sequence variants in two loci resulted in intraspecies resolution of Southeast Asian and Asian genotypes in contrast to a homogenous sequence composition among African isolates. Nucleotide sequence polymorphism in repeat units can enhance discrimination of VNTR loci.
This article was published in J Clin Microbiol
and referenced in Mycobacterial Diseases