alexa Comparative study of how low-level laser therapy and low-intensity pulsed ultrasound affect bone repair in rats.


Journal of Lasers, Optics & Photonics

Author(s): LiraniGalvo AP, Jorgetti V, da Silva OL

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Abstract OBJECTIVE: This study aimed to compare the consequences of low-level laser therapy (LLLT) and low-intensity pulsed ultrasound (LIPUS) on bone repair. BACKGROUND DATA: Many studies have assessed the effects of LLLT and LIPUS on bone repair, but a comparison of them is rare. METHODS: Male Wistar rats (n = 48) with tibial bone osteotomy were used. One group had the osteotomized limb treated with LLLT (GaAlAs laser, 780 nm, 30 mW, 112.5 J/cm(2)) and the second group with LIPUS (1.5 MHz, 30 mW/cm(2)), both for 12 sessions (five times per week); a third group was the control. After 20 days, rats were sacrificed and had their tibias submitted to a bending test or histomorphometric analysis. RESULTS: In the bending test, maximum load at failure of LLLT group was significantly higher (p < 0.05). Bone histomorphometry revealed a significant increase in osteoblast number and surface, and osteoid volume in the LLLT group, and a significant increase in eroded and osteoclast surfaces in the LIPUS group. CONCLUSION: LIPUS enhanced bone repair by promoting bone resorption in the osteotomy area, while LLLT accelerated this process through bone formation. This article was published in Photomed Laser Surg and referenced in Journal of Lasers, Optics & Photonics

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