alexa Comparison of the Clinical Profile and Complications of Mixed Malarial Infections of Plasmodium Falciparum and Plasmodium Vivax versus Plasmodium Falciparum Mono-infection.
Infectious Diseases

Infectious Diseases

Malaria Control & Elimination

Author(s): Joseph V, Varma M, Vidhyasagar S, Mathew A

Abstract Share this page

Abstract OBJECTIVES: This study aimed to compare the clinical presentations and complications in patients having mixed malaria infection of Plasmodium falciparum and Plasmodium vivax with those of patients with malaria due to a P. falciparum mono-infection. METHODS: The medical records of malaria patients admitted to Kasturba Medical College, Manipal, India, during the years 2008-10 were analysed. Inclusion criteria were patients in whom P. falciparum and P. vivax coinfection or P. falciparum mono-infection alone was confirmed on peripheral smear examination. Exclusion criteria were patients in whom P. vivax infection alone was diagnosed on peripheral smear examination. The sample size was twenty patients diagnosed with mixed infection of P. falciparum and P. vivax and 60 patients diagnosed with P. falciparum mono-infection. RESULTS: 35\% of mixed infections had thrombocytopenia as compared to 51.7\% of P. falciparum mono-infections. A total of 5\% of the mixed infections had renal failure as compared to 16.7\% of the falciparum mono-infections. Total bilirubin was raised in 15.8\% of mixed infections and in 46.6\% of falciparum mono-infections. Abnormal liver enzymes were seen in 36.8\% of mixed infections and in 66.6\% of falciparum mono-infections. None of the mixed infections had a parasite index over 2\% while it was present in 28\% of the falciparum mono-infections. CONCLUSION: Patients with mixed infections were found to have a lower incidence of severe complications such as anaemia, thrombocytopenia, liver and renal dysfunction and a lower parasite index. Thus mixed malaria tends to have a more benign course as compared to malaria due to P. falciparum mono-infection.
This article was published in Sultan Qaboos Univ Med J and referenced in Malaria Control & Elimination

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version