Author(s): Almas A, Hameed A, Ahmed B, Islam M
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Abstract OBJECTIVE: To determine compliance, factors affecting compliance to antihypertensive therapy and to compare compliant and non-compliant groups, in a tertiary care setting. STUDY DESIGN: Analytical (cross-sectional) study. PLACE AND DURATION OF STUDY: The outpatient clinics at the Aga Khan University from May 2004 to February 2005. PATIENTS AND METHODS: Two hundred patients presenting to the outpatients clinic were included. All patients 18 years and above, who had stage 1 and 2 hypertension, had one clinic visit to a medicine clinic, 6 months prior to presentation and started on antihypertensive medicines, were included. RESULTS: Sixty six percent were males and 33.5 \% were females. Mean age was 58.1(+/-12) years and mean duration of hypertension was 7.2 (+/- 6.7) years. Fifty-seven percent were compliant and 43 \% were noncompliant. In the noncompliant group, 53.4 \% had mild noncompliance, 24.4 \% had severe non-compliance, while 22\% had moderate noncompliance. Factors of noncompliance were 56.8\% missed doses due to forgetfulness, 12.7\% deliberately missed their doses, 11.6\% could not take the medicine due to side effects, 10.4\% did not take the dose due to increased number of tablets, 4.6\% were not properly counseled by the physician and 3.48\% did not take medicines due to cost issues. The mean systolic blood pressure was 126 +/- 19.2 mmHg in the compliant group while it was 133 +/-16.5 mmHg in the noncompliant group p-value 0.004). The mean diastolic blood pressure in the compliant group was 76 +/- 11.9 mmHg, while in the noncompliant group it was 81.9 +/-10.9 mmHg (p-value 0.001). CONCLUSION: Compliance to antihypertensive therapy in a tertiary care center is significantly good. Forgetfulness was the major reason for noncompliance. The mean blood pressure control was better in the compliant group.
This article was published in J Coll Physicians Surg Pak
and referenced in Journal of Hypertension: Open Access