Author(s): Boland ME, Roper SM, Henry JA
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Abstract Of 165 patients admitted to hospital with acute quinine poisoning 70 (42\%) had visual symptoms. 19 were left with a permanent visual deficit, though none was left completely blind. 5 patients died. Bilateral stellate ganglion block was carried out on 34 patients with impaired visual acuity or blindness, but an improvement of symptoms was reported in only 4 cases. It is concluded that stellate ganglion blockade is not effective enough to justify its regular use in quinine-induced amblyopia. Quinine overdose can have serious consequences, and the drug should not be prescribed indiscriminately.
This article was published in Lancet
and referenced in Journal of Medical Microbiology & Diagnosis