Author(s): Beck M, Claassen M, Aebersold R
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Abstract Extensive proteome discovery projects using a variety of mass spectrometric techniques have identified proteins matching to 50-70\% of the predicted gene models of various species. Comprehensive proteome coverage is desirable for the unbiased comparison of protein quantities between different biological states and for the meaningful comparison of data from multiple samples. Here we discuss the feasibility of this goal in the light of recent technological developments. Copyright © 2010 Elsevier Ltd. All rights reserved.
This article was published in Curr Opin Biotechnol
and referenced in Journal of Chromatography & Separation Techniques