alexa Concise review: challenging the pluripotency of human testis-derived ESC-like cells.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Stem Cell Research & Therapy

Author(s): Tapia N, ArazoBravo MJ, Ko K, Schler HR

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Abstract Several research groups have claimed to have successfully generated pluripotent or multipotent cells from human testis. However, the pluripotent character of those cells with respect to gene expression profile and ability to generate teratomas has been called into question. Here, we critically review these reports and provide insight to guide future studies on the derivation of human pluripotent cells from testicular tissue. Copyright © 2011 AlphaMed Press. This article was published in Stem Cells and referenced in Journal of Stem Cell Research & Therapy

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