Author(s): Antonios SR, Cameron JA, Badr IA, Habash NR, Cotter JB
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Abstract Nine cases (0.41\%) of bacterial and fungal endophthalmitis developed out of a total of 2,210 consecutive penetrating keratoplasties performed between November 1983 and April 1989. Five of the nine cases (0.23\%) had endophthalmitis related to donor tissue contamination. The donor tissue of these cases had a storage time of greater than 5 days. A retrospective analysis of 1,399 consecutive corneoscleral rim cultures showed a contamination rate of 29\%. The most common organisms isolated were Propionibacterium 26\%, diphtheroids 24\%, Staphylococcus epidermidis 22\%, and fungi 9\%. There is a statistically significant increase (p less than 0.005) in the percentage of contaminated donor rims with a preservation time of more than five days. The risk of developing endophthalmitis is 12 times greater with a positive donor rim culture. Prolonged preservation of donor tissue can be a risk factor in developing endophthalmitis.
This article was published in Cornea
and referenced in Journal of Clinical & Experimental Ophthalmology