Author(s): Gay LJ, FeldingHabermann B
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Abstract Extensive experimental evidence shows that platelets support tumour metastasis. The activation of platelets and the coagulation system have a crucial role in the progression of cancer. Within the circulatory system, platelets guard tumour cells from immune elimination and promote their arrest at the endothelium, supporting the establishment of secondary lesions. These contributions of platelets to tumour cell survival and spread suggest platelets as a new avenue for therapy.
This article was published in Nat Rev Cancer
and referenced in Insights in Gynecologic Oncology