alexa COP and clathrin-coated vesicle budding: different pathways, common approaches.
Infectious Diseases

Infectious Diseases

Journal of Tropical Diseases & Public Health

Author(s): McMahon HT, Mills IG

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Abstract Vesicle and tubule transport containers move proteins and lipids from one membrane system to another. Newly forming transport containers frequently have electron-dense coats. Coats coordinate the accumulation of cargo and sculpt the membrane. Recent advances have shown that components of both COP1 and clathrin-adaptor coats share the same structure and the same motif-based cargo recognition and accessory factor recruitment mechanisms, which leads to insights on conserved aspects of coat recruitment, polymerisation and membrane deformation. These themes point to the way in which evolutionarily conserved features underpin these diverse pathways. This article was published in Curr Opin Cell Biol and referenced in Journal of Tropical Diseases & Public Health

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