alexa Coronary artery pattern and age impact exercise performance late after the arterial switch operation.
Cardiology

Cardiology

Journal of Clinical & Experimental Cardiology

Author(s): Pasquali SK, Marino BS, McBride MG, Wernovsky G, Paridon SM

Abstract Share this page

Abstract OBJECTIVE: The impact of coronary artery pattern on exercise performance after the arterial switch operation is unknown. The purpose of this study was to evaluate the relationship between coronary artery pattern and exercise performance late after the arterial switch operation. METHODS: Patients who underwent the arterial switch operation and were referred for exercise stress testing between January of 1996 and April of 2005 were included. Univariate and multivariate analyses were performed to identify risk factors for lower maximum heart rate and percent of predicted peak oxygen consumption. RESULTS: Fifty-three patients were included; 72\% were male. The median age at the arterial switch operation was 5 days (1 day to 3.6 years); 32\% had concurrent ventricular septal defect repair. The time from the arterial switch operation to exercise stress testing was 14.1 years (7.7-20.6 years). There were 37 patients with the usual coronary artery pattern, and 16 patients (30\%) with variant coronary artery patterns. At exercise stress testing, there was no difference in respiratory exchange ratio (1.16 +/- 0.1 for both), indicating similar effort. Compared with patients with the usual coronary artery pattern, patients with variant coronary artery patterns had a significantly lower maximum heart rate (177 +/- 16 beats/min [89\% predicted] vs 186 +/- 11 beats/min [93\% predicted], respectively, P = .04). Percent of predicted peak oxygen consumption was not significantly different between patients with the usual coronary pattern and patients with variant coronary artery patterns (89\% +/- 20\% vs 80\% +/- 17\%, respectively, P = .12). In multivariate analysis, variant coronary artery patterns (P = .03) and ventricular septal defect (P = .004) were predictors of significantly lower maximum heart rate and were associated with a trend toward lower percent of predicted peak oxygen consumption (P < .09). Longer follow-up time was the strongest predictor of lower percent of predicted peak oxygen consumption (P < .001). CONCLUSIONS: Variant coronary artery patterns are associated with chronotropic impairment, and longer follow-up time is the strongest predictor of diminished aerobic capacity late after arterial switch operation. This article was published in J Thorac Cardiovasc Surg and referenced in Journal of Clinical & Experimental Cardiology

Relevant Expert PPTs

Relevant Speaker PPTs

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords