alexa Crescentic transformation in primary membranous glomerulopathy: association with anti-GBM antibody.


Journal of Nephrology & Therapeutics

Author(s): Nayak SG, Satish R

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Abstract Crescentic transformation of primary membranous nephropathy (MN) associated with the development of anti-GBM antibody is a rare cause of acute renal failure in patients with MN. We report a 54-year-old lady, diagnosed to have MN four years earlier, who presented with acute deterioration of renal functions. Renal biopsy revealed circumferential crescents in all glomeruli. Serum anti-GBM antibodies were positive. Despite therapy with plasmapheresis, steroids and oral cyclophosphamide, she did not improve and continues to be dialysis dependent.
This article was published in Saudi J Kidney Dis Transpl and referenced in Journal of Nephrology & Therapeutics

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