Author(s): Brew BJ, Pemberton L, Blennow K, Wallin A, Hagberg L
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Abstract There is concern that AIDS dementia complex (ADC) may be complicated by Alzheimer disease (AD). Because AD presence and risk are related to CSF beta-amyloid(1-42) (Abeta42), total tau (t-tau), and phosphorylated tau (p-tau), the authors examined these in ADC, AD, and controls. ADC had significantly decreased CSF Abeta42 and increased t-tau and p-tau concentrations similar to AD, suggesting that ADC may be associated with AD or an AD-like process.
This article was published in Neurology
and referenced in Journal of Antivirals & Antiretrovirals