Author(s): Capaldo CT, Nusrat A
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Abstract Epithelial and endothelial tight junctions act as a rate-limiting barrier between an organism and its environment. Continuing studies have highlighted the regulation of the tight junction barrier by cytokines. Elucidation of this interplay is vital for both the understanding of physiological tight junction regulation and the etiology of pathological conditions. This review will focus on recent advances in our understanding of the molecular mechanisms of tight junctions modulation by cytokines.
This article was published in Biochim Biophys Acta
and referenced in Journal of Clinical & Cellular Immunology