alexa DAnTE: a statistical tool for quantitative analysis of -omics data.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Computer Science & Systems Biology

Author(s): Polpitiya AD, Qian WJ, Jaitly N, Petyuk VA, Adkins JN,

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Abstract Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly. AVAILABILITY: DAnTE may be downloaded free of charge at http://omics.pnl.gov/software/. SUPPLEMENTARY INFORMATION: An example dataset with instructions on how to perform a series of analysis steps is available at http://omics.pnl.gov/software/
This article was published in Bioinformatics and referenced in Journal of Computer Science & Systems Biology

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