Author(s): Purdy JB, Gafni RI, Reynolds JC, Zeichner S, Hazra R
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Abstract 5 of 6 children infected with human immunodeficiency virus (HIV) receiving Tenofovir disoproxil fumarate (TDF) experienced absolute decreases in bone mineral density (BMD). 2 pre-pubertal subjects experienced >6\% BMD decreases. 1 subject was the smallest child and experienced a 27\% decrease, necessitating withdrawal of TDF. Subsequently, her BMD recovered. Monitoring of children infected with HIV who require treatment with TDF is warranted.
This article was published in J Pediatr
and referenced in Journal of Proteomics & Bioinformatics