alexa Determination of n-octanol water partition coefficient (Kow) of pesticide critical review and comparison of methods
Toxicology

Toxicology

Journal of Clinical Toxicology

Author(s): A Finizio, M Vighi, D Sandroni

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Octanol/water partition coefficients (log Kow) for 87 chemicals representing the main classes of pesticides have been determined by means of three different estimation methods (RP-HPLC, ClogP, calculation from water solubility), and the results have been compared with experimental values (measured mainly with Slow Stirring or Shake Flask methods), collected through a survey of the literature. On the basis of a critical evalution of all available data, a selected value for each pesticide has been proposed. Values and limitations of the three estimation methods has been discussed.

This article was published in Chemosphere and referenced in Journal of Clinical Toxicology

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