alexa Development and preliminary experience with an ease of extractability rating system for prescription opioids.
Pharmaceutical Sciences

Pharmaceutical Sciences

Pharmaceutica Analytica Acta

Author(s): Katz NP, Buse DC, Budman SH, Wing Venuti S, Fernandez KC,

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Abstract One important factor in the abuse potential of an opioid product is the ease with which active drug can be extracted. There are currently no standards for testing or reporting extractability. This article describes the development of an Extractability Rating System for use by the pharmaceutical industry and regulators. Despite several limitations, this effort serves as a call for standardized testing and reporting so that products can be accurately rated, and should help establish goals for drug developers who wish to develop "abuse-resistant" opioid products. This article was published in Drug Dev Ind Pharm and referenced in Pharmaceutica Analytica Acta

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