Author(s): Smallwood RH, Holcombe WM, Walker DC
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Abstract In this paper we take the view that computational models of biological systems should satisfy two conditions - they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be available. A modelling paradigm for developing a predictive computational model of cellular interaction is described, and methods of providing robust validation against biological models are explored, followed by a consideration of software issues.
This article was published in J Mol Histol
and referenced in Journal of Microbial & Biochemical Technology