alexa Development of a short form of Mini-Mental State Examination for the screening of dementia in older adults with a memory complaint: a case control study.


Journal of Alzheimers Disease & Parkinsonism

Author(s): Haubois G, Annweiler C, Launay C, Fantino B, de Decker L,

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Abstract BACKGROUND: Primary care physicians need a brief and accurate screening test of dementia. The objective of this study was to determine whether a short form of Mini-Mental State Examination (SMMSE) was as accurate as the Mini-Mental State Examination (MMSE) in screening dementia. METHODS: Based on case control design study, SMMSE and MMSE were assessed in 184 community-dwelling older adults (mean age 81.3 ± 6.5 years, 71.7\% women) with memory complaint sent by their primary care physician to a memory clinic. Included participants were separated into two groups: cognitively healthy individuals and demented individuals. RESULTS: The trade-off between sensitivity and specificity of the SMMSE for clinically diagnosed dementia was 4. Based on the cut-off value ≤ 4 for SMMSE and a cut-off value ≤ 24 for MMSE, the sensitivity of both tests was similar (89.5\% for SMMSE versus 90.0\% for MMSE), whereas the specificity, the positive predictive values (PPV) and the negative predictive values (NPV) were higher for SMMSE compared to MMSE (85.4 versus 75.5\% for specificity; 95.5\% versus 92.8\% for PPV; 70.0 versus 68.9 for NPV). The positive and negative Likehood Ratio (LR) of SMMSE were higher than those of MMSE (respectively, 6.1 versus 3.7; 8.1 versus 7.7). In addition, odds ratio (OR) for dementia was higher for the SMMSE compared to the MMSE (OR = 49.8 with 95\% confident interval (CI) [18.0; 137.8] versus OR = 28.6 with 95\% CI [11.6; 70.3]). CONCLUSIONS: SMMSE seems to be an efficient short screening test for dementia among community-dwelling older adults with a memory complaint. Further research is needed to confirm its predictive values among unselected primary care older patients.
This article was published in BMC Geriatr and referenced in Journal of Alzheimers Disease & Parkinsonism

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