alexa Diabetes mellitus in older African-Americans, Hispanics, and whites in an academic hospital-based geriatrics practice.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): Ness J, Nassimiha D, Feria MI, Aronow WS

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Abstract BACKGROUND: Diabetes mellitus is a risk factor for target-organ damage/clinical cardiovascular disease in older persons. DESIGN: A retrospective analysis was performed of charts from all older persons (506 men and 1497 women, mean age 80 +/- 8 years) seen during the period from 1 January 1998 to October 1998 at an academic hospital-based geriatrics practice, to investigate the prevalence of diabetes mellitus, and the prevalence, in patients with diabetes, of target-organ damage/clinical cardiovascular disease, hypertension, hypertension or dyslipidaemia, obesity, the drugs used to treat diabetes, and poor glycaemic control. RESULTS: Diabetes mellitus occurred in 127 of 1150 whites (11\%), in 93 of 444 African-Americans (21\%), in 111 of 381 Hispanics (29\%), and in four of 28 Asians (14\%) (P < 0.001 comparing Hispanics with whites and comparing African-Americans with whites; P < 0.01 comparing Hispanics with African-Americans). Of 335 patients with diabetes, 146 (44\%) had coronary disease, 94 (28\%) had stroke or transient cerebral ischaemic attack, 86 (26\%) had peripheral arterial disease, 65 (19\%) had heart failure, 107 (32\%) had nephropathy, 71 (21\%) had retinopathy, 47 (14\%) had neuropathy, 284 (85\%) had target-organ damage/clinical cardiovascular disease, 252 (75\%) had hypertension, 300 (90\%) had hypertension or dyslipidaemia, and 152 (45\%) had obesity. The prevalence of stroke or transient cerebral ischaemic attack was greater in older African-Americans with diabetes mellitus than in older whites with diabetes mellitus (P < 0.02). The prevalence of diabetic nephropathy and of target-organ damage/clinical cardiovascular disease was greater in older African-Americans with diabetes mellitus than in older whites (P < 0.02) and Hispanics (P < 0.05) with diabetes mellitus. Increased concentrations of glycosylated haemoglobin (> 7\%) occurred in 28 of 86 African-Americans (33\%), in 69 of 104 Hispanics (66\%), and in 23 of 118 whites (19\%) (P < 0.001 comparing Hispanics with whites and comparing Hispanics with African-Americans; P < 0.05 comparing African-Americans with whites). CONCLUSIONS: The prevalence of diabetes mellitus in 2003 older persons seen in an academic hospital-based geriatrics practice was 17\% and was greater in Hispanics than in whites or African-Americans, and greater in African-Americans than in whites. The prevalence of target-organ damage/clinical cardiovascular disease was 85\% in 335 older patients with diabetes. The prevalence of stroke or transient cerebral ischaemic attack was greater in older African-Americans with diabetes mellitus than in older whites with the disorder. The prevalence of diabetic nephropathy and of target-organ damage/clinical cardiovascular disease was greater in older African-Americans with diabetes mellitus than in older whites and Hispanics with diabetes mellitus. The prevalence of poor glycaemic control was greater in Hispanics than in whites or African-Americans and greater in African-Americans than in whites.
This article was published in Coron Artery Dis and referenced in Journal of Diabetes & Metabolism

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