alexa Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome.
Reproductive Medicine

Reproductive Medicine

Gynecology & Obstetrics

Author(s): Goodarzi MO, Azziz R

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Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, and its definition remains fluid and controversial. PCOS is characterized by clinical and/or biochemical hyperandrogenism, and is frequently accompanied by ovulatory dysfunction and polycystic ovaries. PCOS is a diagnosis of exclusion, with other androgen excess and related disorders to be excluded. The prevalence of PCOS is 6.5-8.0% of unselected women of reproductive age, using the NIH 1990 criteria. Genetically, PCOS is a common, complex disorder. Despite repeated attempts to identify the putative gene or genes responsible for this disorder, the PCOS gene(s) remain elusive.

This article was published in Best Pract Res Clin Endocrinol Metab. and referenced in Gynecology & Obstetrics

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