alexa Dietary polyphenols, inflammation, and cancer.
Chemistry

Chemistry

Medicinal Chemistry

Author(s): Guo W, Kong E, Meydani M

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Abstract A considerable amount of evidence indicates that tumorigenesis is associated with inflammation. Nuclear factor-kappa B (NF-kappa B), a master regulator of infection and inflammation, has been identified as a key modulator in which inflammation could develop into cancer. Dietary polyphenols have been shown to have anti-inflammatory and anticancer activity partially through inhibition of NF-kappa B activation. This review summarizes the effect of polyphenols on inflammation and cancer; avenanthramides, a unique polyphenol from oats, are especially focused. This article was published in Nutr Cancer and referenced in Medicinal Chemistry

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